M. lignano Ageing
Mlig_RNA_3_7_v3 transcriptome version. Resilience to ageing in the regeneration-capable flatworm Macrostomum lignano.
Mouton S*, Grudniewska M*, Guryev V, Berezikov E. Aging Cell 17:e12739 (2018). Home Download

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Found 387 results for log2(M26/M2) >= 1 and fdr <= 0.01. Showing entries 1-20.

Graph Cluster Transcripts Mean logCPM logFC M26/M2 FDR M26/M2 Classification Human genes C.elegans genes Annotation
1. MligTCv3c-562.3180 Mlig007010.g20, Mlig007010.g19, Mlig007010.g16, Mlig007010.g18, Mlig007010.g17, Mlig007010.g12, Mlig007010.g7, Mlig007010.g4, Mlig007010.g3 10.45 2.417 0

Mlig007010.g20 {Length: 3443} {UniRef: UniRef50_A0A1I8IMX1, Reticulon-like protein n=1 Tax=Macrostomum lignano TaxID=282301 RepID=A0A1I8IMX1_9PLAT, [Score=78.6, Expect=3e-16]}

Mlig007010.g19 {Length: 448} {NoTransDecoderORF} {RNA1509_64}

Mlig007010.g16 {Length: 414} {NoTransDecoderORF} {RNA1509_64}

Mlig007010.g18 {Length: 413} {NoTransDecoderORF} {RNA1509_64}

Mlig007010.g17 {Length: 408} {NoTransDecoderORF} {RNA1509_64}

Mlig007010.g12 {Length: 408} {NoTransDecoderORF} {RNA1509_64}

Mlig007010.g7 {Length: 19732} {UniRef: UniRef50_A0A1I8IMX1, Reticulon-like protein n=1 Tax=Macrostomum lignano TaxID=282301 RepID=A0A1I8IMX1_9PLAT, [Score=78.6, Expect=3e-16]}

Mlig007010.g4 {Length: 414} {NoTransDecoderORF} {RNA1509_5074}

Mlig007010.g3 {Length: 398} {NoTransDecoderORF} {RNA1509_5074}
2. MligTCv3c-4830.1 Mlig033458.g2, Mlig033458.g1 10.32 1.349 0

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 GM2A

Mlig033458.g2 {Length: 708} {TRANSSPLICED} {Pfam: ML domain [PF02221.13, score=46.6]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=62.0, Expect=2e-11]} {Smed: dd_Smed_v6_214_1_1, [RH, Score=80.9, Expect=3e-19]} {Smes: dd_Smes_v1_24451_1_1, [RH, Score=80.5, Expect=5e-19]} {UniRef: UniRef50_K1QZB5, Ganglioside GM2 activator n=1 Tax=Crassostrea gigas TaxID=29159 RepID=K1QZB5_CRAGI, [Score=91.7, Expect=2e-20]} {RNA1509_43}

Mlig033458.g1 {Length: 708} {TRANSSPLICED} {Pfam: ML domain [PF02221.13, score=46.6]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=62.0, Expect=2e-11]} {Smed: dd_Smed_v6_214_1_1, [RH, Score=80.9, Expect=3e-19]} {Smes: dd_Smes_v1_24451_1_1, [RH, Score=80.5, Expect=5e-19]} {UniRef: UniRef50_K1QZB5, Ganglioside GM2 activator n=1 Tax=Crassostrea gigas TaxID=29159 RepID=K1QZB5_CRAGI, [Score=91.7, Expect=2e-20]} {RNA1509_43}
3. MligTCv3c-14051.2 Mlig018102.g1 9.46 1.493 0

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 Mlig018102.g1 {Length: 1677} {SignalP} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.9, score=157.1]; Group 7 allergen [PF16984.3, score=99.3]} {Dmel: FBgn0031538, CG3246, , [Score=85.9, Expect=8e-18]} {Smed: dd_Smed_v6_888_0_1, [Score=71.2, Expect=6e-14]} {Smes: dd_Smes_v1_78416_1_1, [Score=70.9, Expect=8e-14]} {UniRef: UniRef50_UPI0006B08364, PREDICTED: uncharacterized protein LOC106459993 n=2 Tax=Limulus polyphemus TaxID=6850 RepID=UPI0006B08364, [Score=162, Expect=2e-42]} {RNA1509_148, RNA1509_27036, RNA1509_47664} {WURTZEL: Gut [dd_Smed_v6_888_0_1, NA]}
4. MligTCv3c-4830.0 Mlig033458.g3 9.42 1.368 0 GM2A Mlig033458.g3 {Length: 858} {Pfam: ML domain [PF02221.13, score=46.6]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=62.0, Expect=2e-11]} {Smed: dd_Smed_v6_214_1_1, [RH, Score=80.9, Expect=3e-19]} {Smes: dd_Smes_v1_24451_1_1, [RH, Score=80.5, Expect=5e-19]} {UniRef: UniRef50_K1QZB5, Ganglioside GM2 activator n=1 Tax=Crassostrea gigas TaxID=29159 RepID=K1QZB5_CRAGI, [Score=91.7, Expect=2e-20]} {RNA1509_1066, RNA1509_14446, RNA1509_43, RNA1509_8277}
5. MligTCv3c-12855.0 Mlig001709.g6 9.13 1.418 0

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 GM2A Mlig001709.g6 {Length: 1054} {SignalP} {Pfam: ML domain [PF02221.13, score=40.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=51.2, Expect=8e-08]} {Smed: dd_Smed_v6_214_1_1, [Score=56.2, Expect=3e-10]} {Smes: dd_Smes_v1_24451_1_1, [Score=52.4, Expect=1e-08]} {UniRef: UniRef50_K1QZB5, Ganglioside GM2 activator n=1 Tax=Crassostrea gigas TaxID=29159 RepID=K1QZB5_CRAGI, [Score=99.8, Expect=6e-24]; UniRef50_UPI000696CE1F, PREDICTED: ganglioside GM2 activator-like n=1 Tax=Lingula unguis TaxID=7574 RepID=UPI000696CE1F, [Score=99.4, Expect=6e-24]} {RNA1509_4662, RNA1509_960}
6. MligTCv3c-7268.2 Mlig009601.g2 8.93 1.079 0

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 TMPRSS9 try-1 Mlig009601.g2 {Length: 1582} {SignalP} {Pfam: Trypsin [PF00089.24, score=249.9]; CUB domain [PF00431.18, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.16, score=46.9]; Trypsin-like peptidase domain [PF13365.4, score=33.2]; Domain of unknown function (DUF1986) [PF09342.9, score=27.4]} {Human: ENSG00000178297, TMPRSS9, transmembrane protease, serine 9, [RH, Score=207, Expect=5e-61]} {Dmel: FBgn0033192, Corin, Corin, [RH, Score=174, Expect=4e-47]; FBgn0265011, Np, Notopleural, [RH, Score=172, Expect=1e-46]} {Celegans: WBGene00006619, try-1, Caenorhabditis elegans Protein TRY-1 (try-1) mRNA, complete cds., [RH, Score=150, Expect=3e-42]} {Smed: dd_Smed_v6_790_0_1, [Score=162, Expect=2e-43]; dd_Smed_v6_1926_0_1, [Score=158, Expect=8e-42]} {Smes: dd_Smes_v1_41792_3_1, [Score=239, Expect=2e-73]; dd_Smes_v1_22443_1_2, [Score=229, Expect=1e-67]} {Smans: Smp_103680.1, [RH, Score=173, Expect=8e-51]} {UniRef: UniRef50_UPI000697B76B, PREDICTED: bone morphogenetic protein 1-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI000697B76B, [Score=350, Expect=1e-110]; UniRef50_UPI000947B8F3, UPI000947B8F3 related cluster n=1 Tax=unknown TaxID= RepID=UPI000947B8F3, [Score=347, Expect=1e-106]} {RNA1509_10189, RNA1509_12560, RNA1509_254, RNA1509_40712, RNA1509_536}
7. MligTCv3c-15475.1 Mlig019930.g1 8.61 1.271 0

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 Mlig019930.g1 {Length: 944} {RNA1509_347, RNA1509_863}
8. MligTCv3c-7268.1 Mlig009601.g1 8.53 1.03 0

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 TMPRSS9 try-1 Mlig009601.g1 {Length: 1621} {SignalP} {Pfam: Trypsin [PF00089.24, score=251.2]; CUB domain [PF00431.18, score=104.4]; Low-density lipoprotein receptor domain class A [PF00057.16, score=46.9]; Trypsin-like peptidase domain [PF13365.4, score=33.3]; Domain of unknown function (DUF1986) [PF09342.9, score=24.8]} {Human: ENSG00000178297, TMPRSS9, transmembrane protease, serine 9, [RH, Score=209, Expect=2e-61]} {Dmel: FBgn0033192, Corin, Corin, [RH, Score=173, Expect=6e-47]; FBgn0265011, Np, Notopleural, [RH, Score=172, Expect=2e-46]} {Celegans: WBGene00006619, try-1, Caenorhabditis elegans Protein TRY-1 (try-1) mRNA, complete cds., [RH, Score=152, Expect=8e-43]} {Smed: dd_Smed_v6_790_0_1, [Score=165, Expect=4e-44]; dd_Smed_v6_1926_0_1, [Score=160, Expect=8e-43]} {Smes: dd_Smes_v1_41792_3_1, [Score=240, Expect=4e-74]} {Smans: Smp_103680.1, [RH, Score=172, Expect=2e-50]} {UniRef: UniRef50_UPI000697B76B, PREDICTED: bone morphogenetic protein 1-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI000697B76B, [Score=351, Expect=1e-110]} {RNA1509_16494, RNA1509_1686, RNA1509_25938, RNA1509_423, RNA1509_8940} {WURTZEL: Gamma neoblasts [dd_Smed_v6_790_0_1, protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)]} {WURTZEL: Gut [dd_Smed_v6_1926_0_1, protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)]}
9. MligTCv3c-12855.3 Mlig001709.g4 7.94 1.08 0

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 GM2A Mlig001709.g4 {Length: 745} {SignalP} {Pfam: ML domain [PF02221.13, score=39.6]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=49.3, Expect=5e-07]} {Smed: dd_Smed_v6_214_1_1, [Score=53.1, Expect=6e-09]} {Smes: dd_Smes_v1_24451_1_1, [Score=48.9, Expect=2e-07]} {UniRef: UniRef50_K1QZB5, Ganglioside GM2 activator n=1 Tax=Crassostrea gigas TaxID=29159 RepID=K1QZB5_CRAGI, [Score=99.8, Expect=7e-24]; UniRef50_UPI000696CE1F, PREDICTED: ganglioside GM2 activator-like n=1 Tax=Lingula unguis TaxID=7574 RepID=UPI000696CE1F, [Score=99.0, Expect=1e-23]} {RNA1509_1350}
10. MligTCv3c-562.5850 Mlig001791.g6 7.88 1.339 0 Mlig001791.g6 {Length: 431} {SignalP} {RNA1509_17768}
11. MligTCv3c-7268.0 Mlig029509.g1 7.85 1.28 0

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 TMPRSS9 try-1 Mlig029509.g1 {Length: 1604} {SignalP} {Pfam: Trypsin [PF00089.24, score=249.9]; CUB domain [PF00431.18, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.16, score=46.9]; Trypsin-like peptidase domain [PF13365.4, score=33.2]; Domain of unknown function (DUF1986) [PF09342.9, score=27.4]} {Human: ENSG00000178297, TMPRSS9, transmembrane protease, serine 9, [RH, Score=207, Expect=5e-61]} {Dmel: FBgn0033192, Corin, Corin, [RH, Score=174, Expect=4e-47]; FBgn0265011, Np, Notopleural, [RH, Score=172, Expect=1e-46]} {Celegans: WBGene00006619, try-1, Caenorhabditis elegans Protein TRY-1 (try-1) mRNA, complete cds., [RH, Score=150, Expect=3e-42]} {Smed: dd_Smed_v6_790_0_1, [Score=162, Expect=2e-43]; dd_Smed_v6_1926_0_1, [Score=158, Expect=8e-42]} {Smes: dd_Smes_v1_41792_3_1, [Score=239, Expect=2e-73]; dd_Smes_v1_22443_1_2, [Score=229, Expect=1e-67]} {Smans: Smp_103680.1, [RH, Score=173, Expect=8e-51]} {UniRef: UniRef50_UPI000697B76B, PREDICTED: bone morphogenetic protein 1-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI000697B76B, [Score=350, Expect=1e-110]; UniRef50_UPI000947B8F3, UPI000947B8F3 related cluster n=1 Tax=unknown TaxID= RepID=UPI000947B8F3, [Score=347, Expect=1e-106]} {RNA1509_254, RNA1509_4892} {WURTZEL: Gamma neoblasts [dd_Smed_v6_790_0_1, protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)]} {WURTZEL: Gut [dd_Smed_v6_1926_0_1, protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)]}
12. MligTCv3c-562.5847 Mlig027710.g1 7.81 1.314 0

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 MAOA amx-2 Mlig027710.g1 {Length: 2838} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.22, score=152.0]; NAD(P)-binding Rossmann-like domain [PF13450.4, score=41.5]; FAD dependent oxidoreductase [PF01266.22, score=21.1]; Lycopene cyclase protein [PF05834.10, score=19.2]; FAD binding domain [PF00890.22, score=17.8]} {Human: ENSG00000189221, MAOA, monoamine oxidase A, [Score=178, Expect=3e-49]} {Dmel: FBgn0035943, CG5653, , [Score=50.8, Expect=2e-06]} {Celegans: WBGene00000138, amx-2, Caenorhabditis elegans Protein AMX-2 (amx-2) mRNA, complete cds., [Score=62.8, Expect=3e-10]} {Smed: dd_Smed_v6_7098_0_2, [Score=265, Expect=7e-83]; dd_Smed_v6_6606_1_1, [Score=253, Expect=3e-78]} {Smes: dd_Smes_v1_32006_1_3, [Score=267, Expect=1e-83]} {Smans: Smp_162940.1, [Score=47.0, Expect=1e-05]} {UniRef: UniRef50_A0A1I8IQ98, Amine oxidase n=3 Tax=Macrostomum lignano TaxID=282301 RepID=A0A1I8IQ98_9PLAT, [Score=545, Expect=0.0]} {RNA1509_42140}
13. MligTCv3c-562.5837 Mlig027710.g8 7.59 1.319 0

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 MAOA amx-2 Mlig027710.g8 {Length: 3490} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.22, score=150.6]; NAD(P)-binding Rossmann-like domain [PF13450.4, score=41.6]; FAD dependent oxidoreductase [PF01266.22, score=20.3]; Lycopene cyclase protein [PF05834.10, score=20.1]; FAD binding domain [PF00890.22, score=17.8]} {Human: ENSG00000189221, MAOA, monoamine oxidase A, [Score=170, Expect=3e-46]} {Dmel: FBgn0035943, CG5653, , [Score=50.8, Expect=2e-06]} {Celegans: WBGene00000138, amx-2, Caenorhabditis elegans Protein AMX-2 (amx-2) mRNA, complete cds., [Score=62.8, Expect=3e-10]} {Smed: dd_Smed_v6_7098_0_2, [Score=256, Expect=1e-79]} {Smes: dd_Smes_v1_32006_1_3, [Score=259, Expect=2e-80]} {Smans: Smp_162940.1, [Score=47.4, Expect=9e-06]} {UniRef: UniRef50_A0A1I8IQ98, Amine oxidase n=3 Tax=Macrostomum lignano TaxID=282301 RepID=A0A1I8IQ98_9PLAT, [Score=493, Expect=1e-172]} {RNA1509_8918}
14. MligTCv3c-15260.1 Mlig021288.g2, Mlig021288.g1 7.59 2.033 0

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Mlig021288.g2 {Length: 1597} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.9, score=159.6]} {Dmel: FBgn0039483, CG14259, , [Score=48.5, Expect=3e-06]; FBgn0038394, CG10264, , [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_888_0_1, [RH, Score=60.1, Expect=1e-10]} {Smes: dd_Smes_v1_78416_1_1, [RH, Score=60.5, Expect=1e-10]} {UniRef: UniRef50_UPI0006B10940, PREDICTED: uncharacterized protein LOC106475944 n=1 Tax=Limulus polyphemus TaxID=6850 RepID=UPI0006B10940, [Score=88.2, Expect=2e-18]} {RNA1509_247}

Mlig021288.g1 {Length: 1629} {SignalP} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.9, score=163.0]; Group 7 allergen [PF16984.3, score=95.7]} {Dmel: FBgn0031538, CG3246, , [RH, Score=68.9, Expect=3e-12]} {Smed: dd_Smed_v6_888_0_1, [RH, Score=59.3, Expect=6e-10]} {Smes: dd_Smes_v1_78416_1_1, [RH, Score=59.3, Expect=7e-10]} {UniRef: UniRef50_UPI0006B08364, PREDICTED: uncharacterized protein LOC106459993 n=2 Tax=Limulus polyphemus TaxID=6850 RepID=UPI0006B08364, [Score=132, Expect=1e-31]} {RNA1509_247} {WURTZEL: Gut [dd_Smed_v6_888_0_1, NA]}
15. MligTCv3c-12855.2 Mlig001709.g5 7.49 1.386 0 GM2A Mlig001709.g5 {Length: 1584} {SignalP} {Pfam: ML domain [PF02221.13, score=40.7]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=51.6, Expect=7e-08]} {Smed: dd_Smed_v6_214_1_1, [Score=56.2, Expect=4e-10]} {Smes: dd_Smes_v1_24451_1_1, [Score=52.0, Expect=1e-08]} {UniRef: UniRef50_K1QZB5, Ganglioside GM2 activator n=1 Tax=Crassostrea gigas TaxID=29159 RepID=K1QZB5_CRAGI, [Score=101, Expect=1e-24]} {RNA1509_180, RNA1509_30371, RNA1509_960}
16. MligTCv3c-16860.0 Mlig013864.g3 7.43 1.151 0

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 Mlig013864.g3 {Length: 664}
17. MligTCv3c-9248.0 Mlig024556.g3 7.36 1.601 0

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 CPA2 T06A4.1 Mlig024556.g3 {Length: 1497} {SignalP} {Pfam: Zinc carboxypeptidase [PF00246.22, score=261.7]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2 (pancreatic), [Score=216, Expect=3e-65]} {Dmel: FBgn0032144, CG17633, , [RH, Score=230, Expect=1e-70]} {Celegans: WBGene00020281, T06A4.1, Caenorhabditis elegans Protein T06A4.1, isoform a (T06A4.1) mRNA, complete cds., [Score=209, Expect=1e-61]} {Smed: dd_Smed_v6_2541_0_1, [RH, Score=254, Expect=1e-80]; dd_Smed_v6_1412_0_1, [RH, Score=248, Expect=4e-78]} {Smes: dd_Smes_v1_78649_1_1, [RH, Score=254, Expect=2e-80]; dd_Smes_v1_77824_1_1, [RH, Score=250, Expect=1e-78]} {Smans: Smp_088270.1, [Score=162, Expect=8e-46]} {UniRef: UniRef50_UPI0006991870, PREDICTED: carboxypeptidase B-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI0006991870, [Score=275, Expect=2e-85]} {RNA1509_334}
18. MligTCv3c-15260.0 Mlig021288.g3 7.33 1.917 0

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 Mlig021288.g3 {Length: 1598} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.9, score=162.1]; Group 7 allergen [PF16984.3, score=95.5]} {Dmel: FBgn0031538, CG3246, , [RH, Score=68.9, Expect=3e-12]} {Smed: dd_Smed_v6_888_0_1, [RH, Score=59.7, Expect=5e-10]} {Smes: dd_Smes_v1_78416_1_1, [RH, Score=59.3, Expect=7e-10]} {UniRef: UniRef50_UPI0006B08364, PREDICTED: uncharacterized protein LOC106459993 n=2 Tax=Limulus polyphemus TaxID=6850 RepID=UPI0006B08364, [Score=132, Expect=2e-31]} {RNA1509_1643} {WURTZEL: Gut [dd_Smed_v6_888_0_1, NA]}
19. MligTCv3c-16701.0 Mlig026472.g1 7.09 1.282 0

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 ZAN T01D3.6 Mlig026472.g1 {Length: 23210} {SignalP} {Pfam: von Willebrand factor type D domain [PF00094.23, score=74.8]} {Human: ENSG00000146839, ZAN, zonadhesin, [Score=149, Expect=1e-34]} {Dmel: FBgn0000395, cv-2, crossveinless 2, [Score=91.7, Expect=8e-18]} {Celegans: WBGene00011330, T01D3.6, Caenorhabditis elegans Protein T01D3.6, isoform a (T01D3.6) mRNA, complete cds., [Score=101, Expect=8e-21]} {Smed: dd_Smed_v6_1636_0_1, [Score=314, Expect=1e-85]; dd_Smed_v6_91_0_1, [Score=301, Expect=4e-81]} {Smes: dd_Smes_v1_8166_1_1, [Score=311, Expect=3e-84]; dd_Smes_v1_28490_1_1, [Score=300, Expect=4e-81]} {Smans: Smp_157690.1, [Score=114, Expect=6e-25]} {UniRef: UniRef50_UPI00065BE610, PREDICTED: zonadhesin-like n=1 Tax=Aplysia californica TaxID=6500 RepID=UPI00065BE610, [Score=192, Expect=5e-46]} {RNA1509_10412, RNA1509_111, RNA1509_11187, RNA1509_18431, RNA1509_23585, RNA1509_28856, RNA1509_32758, RNA1509_35521, RNA1509_36355, RNA1509_37743, RNA1509_39781, RNA1509_43740, RNA1509_46375, RNA1509_48634, RNA1509_55184, RNA1509_55901, RNA1509_55993, RNA1509_58762, RNA1509_59264}
20. MligTCv3c-9248.1 Mlig024556.g2 7.06 1.541 0

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 CPA2 T06A4.1 Mlig024556.g2 {Length: 1497} {SignalP} {Pfam: Zinc carboxypeptidase [PF00246.22, score=260.6]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2 (pancreatic), [Score=215, Expect=5e-65]} {Dmel: FBgn0032144, CG17633, , [RH, Score=231, Expect=2e-71]} {Celegans: WBGene00020281, T06A4.1, Caenorhabditis elegans Protein T06A4.1, isoform a (T06A4.1) mRNA, complete cds., [Score=210, Expect=9e-62]} {Smed: dd_Smed_v6_2541_0_1, [RH, Score=254, Expect=3e-80]; dd_Smed_v6_1412_0_1, [RH, Score=247, Expect=2e-77]} {Smes: dd_Smes_v1_78649_1_1, [RH, Score=254, Expect=3e-80]; dd_Smes_v1_77824_1_1, [RH, Score=248, Expect=7e-78]} {Smans: Smp_088270.1, [Score=160, Expect=5e-45]} {UniRef: UniRef50_UPI0006991870, PREDICTED: carboxypeptidase B-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI0006991870, [Score=277, Expect=2e-86]} {RNA1509_334, RNA1509_3364}
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