M. lignano Ageing
Mlig_RNA_3_7_v3 transcriptome version. Resilience to ageing in the regeneration-capable flatworm Macrostomum lignano.
Mouton S*, Grudniewska M*, Guryev V, Berezikov E. Aging Cell 17:e12739 (2018). Home Download

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Found 107 results for path Up-Up-Up. Showing entries 1-20.

Graph Cluster Transcripts Mean logCPM logFC M26/M2 FDR M26/M2 Classification Human genes C.elegans genes Annotation
1. MligTCv3c-8356.0 Mlig009159.g3 10.42 0.849 0.000

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 Mlig009159.g3 {Length: 1653} {SignalP} {RNA1509_16, RNA1509_21703, RNA1509_9336}
2. MligTCv3c-12128.4 Mlig032866.g3 9.86 0.666 0.000

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 PSMD4 rpn-10 Mlig032866.g3 {Length: 3979} {TRANSSPLICED} {Pfam: von Willebrand factor type A domain [PF13519.4, score=59.8]; Ubiquitin interaction motif [PF02809.18, score=23.8]} {Human: ENSG00000159352, PSMD4, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4, [RH, Score=303, Expect=1e-100]} {Dmel: FBgn0015283, Rpn10, Regulatory particle non-ATPase 10, [RH, Score=267, Expect=1e-85]} {Celegans: WBGene00004466, rpn-10, Caenorhabditis elegans Protein RPN-10 (rpn-10) mRNA, complete cds., [RH, Score=201, Expect=6e-61]} {Smed: dd_Smed_v6_1231_0_1, [RH, Score=216, Expect=9e-67]} {Smes: dd_Smes_v1_5052_1_1, [RH, Score=217, Expect=9e-67]; dd_Smes_v1_16684_1_1, [RH, Score=210, Expect=2e-64]} {Smans: Smp_000740.2, [RH, Score=298, Expect=4e-98]} {UniRef: UniRef50_UPI000329ADA6, PREDICTED: 26S proteasome non-ATPase regulatory subunit 4 n=2 Tax=Pseudocrenilabrinae TaxID=318546 RepID=UPI000329ADA6, [Score=305, Expect=2e-98]; UniRef50_O35226-3, Isoform Rpn10C of 26S proteasome non-ATPase regulatory subunit 4 n=97 Tax=Bilateria TaxID=33213 RepID=O35226-3, [Score=302, Expect=2e-97]} {RNA1509_14233, RNA1509_14370, RNA1509_19280, RNA1509_20122, RNA1509_22590, RNA1509_25292, RNA1509_26944, RNA1509_2886, RNA1509_37644, RNA1509_532, RNA1509_55615, RNA1509_87, RNA1509_8983}
3. MligTCv3c-14051.2 Mlig018102.g1 9.46 1.493 0.000

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 Mlig018102.g1 {Length: 1677} {SignalP} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.9, score=157.1]; Group 7 allergen [PF16984.3, score=99.3]} {Dmel: FBgn0031538, CG3246, , [Score=85.9, Expect=8e-18]} {Smed: dd_Smed_v6_888_0_1, [Score=71.2, Expect=6e-14]} {Smes: dd_Smes_v1_78416_1_1, [Score=70.9, Expect=8e-14]} {UniRef: UniRef50_UPI0006B08364, PREDICTED: uncharacterized protein LOC106459993 n=2 Tax=Limulus polyphemus TaxID=6850 RepID=UPI0006B08364, [Score=162, Expect=2e-42]} {RNA1509_148, RNA1509_27036, RNA1509_47664} {WURTZEL: Gut [dd_Smed_v6_888_0_1, NA]}
4. MligTCv3c-12128.3 Mlig025766.g1 9.43 0.707 0.000

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 Mlig025766.g1 {Length: 1265} {RNA1509_12033, RNA1509_26999, RNA1509_58357}
5. MligTCv3c-7268.2 Mlig009601.g2 8.93 1.079 0.000

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 TMPRSS9 try-1 Mlig009601.g2 {Length: 1582} {SignalP} {Pfam: Trypsin [PF00089.24, score=249.9]; CUB domain [PF00431.18, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.16, score=46.9]; Trypsin-like peptidase domain [PF13365.4, score=33.2]; Domain of unknown function (DUF1986) [PF09342.9, score=27.4]} {Human: ENSG00000178297, TMPRSS9, transmembrane protease, serine 9, [RH, Score=207, Expect=5e-61]} {Dmel: FBgn0033192, Corin, Corin, [RH, Score=174, Expect=4e-47]; FBgn0265011, Np, Notopleural, [RH, Score=172, Expect=1e-46]} {Celegans: WBGene00006619, try-1, Caenorhabditis elegans Protein TRY-1 (try-1) mRNA, complete cds., [RH, Score=150, Expect=3e-42]} {Smed: dd_Smed_v6_790_0_1, [Score=162, Expect=2e-43]; dd_Smed_v6_1926_0_1, [Score=158, Expect=8e-42]} {Smes: dd_Smes_v1_41792_3_1, [Score=239, Expect=2e-73]; dd_Smes_v1_22443_1_2, [Score=229, Expect=1e-67]} {Smans: Smp_103680.1, [RH, Score=173, Expect=8e-51]} {UniRef: UniRef50_UPI000697B76B, PREDICTED: bone morphogenetic protein 1-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI000697B76B, [Score=350, Expect=1e-110]; UniRef50_UPI000947B8F3, UPI000947B8F3 related cluster n=1 Tax=unknown TaxID= RepID=UPI000947B8F3, [Score=347, Expect=1e-106]} {RNA1509_10189, RNA1509_12560, RNA1509_254, RNA1509_40712, RNA1509_536}
6. MligTCv3c-15475.1 Mlig019930.g1 8.61 1.271 0.000

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 Mlig019930.g1 {Length: 944} {RNA1509_347, RNA1509_863}
7. MligTCv3c-7268.1 Mlig009601.g1 8.53 1.030 0.000

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 TMPRSS9 try-1 Mlig009601.g1 {Length: 1621} {SignalP} {Pfam: Trypsin [PF00089.24, score=251.2]; CUB domain [PF00431.18, score=104.4]; Low-density lipoprotein receptor domain class A [PF00057.16, score=46.9]; Trypsin-like peptidase domain [PF13365.4, score=33.3]; Domain of unknown function (DUF1986) [PF09342.9, score=24.8]} {Human: ENSG00000178297, TMPRSS9, transmembrane protease, serine 9, [RH, Score=209, Expect=2e-61]} {Dmel: FBgn0033192, Corin, Corin, [RH, Score=173, Expect=6e-47]; FBgn0265011, Np, Notopleural, [RH, Score=172, Expect=2e-46]} {Celegans: WBGene00006619, try-1, Caenorhabditis elegans Protein TRY-1 (try-1) mRNA, complete cds., [RH, Score=152, Expect=8e-43]} {Smed: dd_Smed_v6_790_0_1, [Score=165, Expect=4e-44]; dd_Smed_v6_1926_0_1, [Score=160, Expect=8e-43]} {Smes: dd_Smes_v1_41792_3_1, [Score=240, Expect=4e-74]} {Smans: Smp_103680.1, [RH, Score=172, Expect=2e-50]} {UniRef: UniRef50_UPI000697B76B, PREDICTED: bone morphogenetic protein 1-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI000697B76B, [Score=351, Expect=1e-110]} {RNA1509_16494, RNA1509_1686, RNA1509_25938, RNA1509_423, RNA1509_8940} {WURTZEL: Gamma neoblasts [dd_Smed_v6_790_0_1, protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)]} {WURTZEL: Gut [dd_Smed_v6_1926_0_1, protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)]}
8. MligTCv3c-7268.0 Mlig029509.g1 7.85 1.280 0.000

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 TMPRSS9 try-1 Mlig029509.g1 {Length: 1604} {SignalP} {Pfam: Trypsin [PF00089.24, score=249.9]; CUB domain [PF00431.18, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.16, score=46.9]; Trypsin-like peptidase domain [PF13365.4, score=33.2]; Domain of unknown function (DUF1986) [PF09342.9, score=27.4]} {Human: ENSG00000178297, TMPRSS9, transmembrane protease, serine 9, [RH, Score=207, Expect=5e-61]} {Dmel: FBgn0033192, Corin, Corin, [RH, Score=174, Expect=4e-47]; FBgn0265011, Np, Notopleural, [RH, Score=172, Expect=1e-46]} {Celegans: WBGene00006619, try-1, Caenorhabditis elegans Protein TRY-1 (try-1) mRNA, complete cds., [RH, Score=150, Expect=3e-42]} {Smed: dd_Smed_v6_790_0_1, [Score=162, Expect=2e-43]; dd_Smed_v6_1926_0_1, [Score=158, Expect=8e-42]} {Smes: dd_Smes_v1_41792_3_1, [Score=239, Expect=2e-73]; dd_Smes_v1_22443_1_2, [Score=229, Expect=1e-67]} {Smans: Smp_103680.1, [RH, Score=173, Expect=8e-51]} {UniRef: UniRef50_UPI000697B76B, PREDICTED: bone morphogenetic protein 1-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI000697B76B, [Score=350, Expect=1e-110]; UniRef50_UPI000947B8F3, UPI000947B8F3 related cluster n=1 Tax=unknown TaxID= RepID=UPI000947B8F3, [Score=347, Expect=1e-106]} {RNA1509_254, RNA1509_4892} {WURTZEL: Gamma neoblasts [dd_Smed_v6_790_0_1, protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)]} {WURTZEL: Gut [dd_Smed_v6_1926_0_1, protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)]}
9. MligTCv3c-15260.1 Mlig021288.g2, Mlig021288.g1 7.59 2.033 0.000

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Mlig021288.g2 {Length: 1597} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.9, score=159.6]} {Dmel: FBgn0039483, CG14259, , [Score=48.5, Expect=3e-06]; FBgn0038394, CG10264, , [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_888_0_1, [RH, Score=60.1, Expect=1e-10]} {Smes: dd_Smes_v1_78416_1_1, [RH, Score=60.5, Expect=1e-10]} {UniRef: UniRef50_UPI0006B10940, PREDICTED: uncharacterized protein LOC106475944 n=1 Tax=Limulus polyphemus TaxID=6850 RepID=UPI0006B10940, [Score=88.2, Expect=2e-18]} {RNA1509_247}

Mlig021288.g1 {Length: 1629} {SignalP} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.9, score=163.0]; Group 7 allergen [PF16984.3, score=95.7]} {Dmel: FBgn0031538, CG3246, , [RH, Score=68.9, Expect=3e-12]} {Smed: dd_Smed_v6_888_0_1, [RH, Score=59.3, Expect=6e-10]} {Smes: dd_Smes_v1_78416_1_1, [RH, Score=59.3, Expect=7e-10]} {UniRef: UniRef50_UPI0006B08364, PREDICTED: uncharacterized protein LOC106459993 n=2 Tax=Limulus polyphemus TaxID=6850 RepID=UPI0006B08364, [Score=132, Expect=1e-31]} {RNA1509_247} {WURTZEL: Gut [dd_Smed_v6_888_0_1, NA]}
10. MligTCv3c-16860.0 Mlig013864.g3 7.43 1.151 0.000

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 Mlig013864.g3 {Length: 664}
11. MligTCv3c-9248.0 Mlig024556.g3 7.36 1.601 0.000

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 CPA2 T06A4.1 Mlig024556.g3 {Length: 1497} {SignalP} {Pfam: Zinc carboxypeptidase [PF00246.22, score=261.7]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2 (pancreatic), [Score=216, Expect=3e-65]} {Dmel: FBgn0032144, CG17633, , [RH, Score=230, Expect=1e-70]} {Celegans: WBGene00020281, T06A4.1, Caenorhabditis elegans Protein T06A4.1, isoform a (T06A4.1) mRNA, complete cds., [Score=209, Expect=1e-61]} {Smed: dd_Smed_v6_2541_0_1, [RH, Score=254, Expect=1e-80]; dd_Smed_v6_1412_0_1, [RH, Score=248, Expect=4e-78]} {Smes: dd_Smes_v1_78649_1_1, [RH, Score=254, Expect=2e-80]; dd_Smes_v1_77824_1_1, [RH, Score=250, Expect=1e-78]} {Smans: Smp_088270.1, [Score=162, Expect=8e-46]} {UniRef: UniRef50_UPI0006991870, PREDICTED: carboxypeptidase B-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI0006991870, [Score=275, Expect=2e-85]} {RNA1509_334}
12. MligTCv3c-15260.0 Mlig021288.g3 7.33 1.917 0.000

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 Mlig021288.g3 {Length: 1598} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.9, score=162.1]; Group 7 allergen [PF16984.3, score=95.5]} {Dmel: FBgn0031538, CG3246, , [RH, Score=68.9, Expect=3e-12]} {Smed: dd_Smed_v6_888_0_1, [RH, Score=59.7, Expect=5e-10]} {Smes: dd_Smes_v1_78416_1_1, [RH, Score=59.3, Expect=7e-10]} {UniRef: UniRef50_UPI0006B08364, PREDICTED: uncharacterized protein LOC106459993 n=2 Tax=Limulus polyphemus TaxID=6850 RepID=UPI0006B08364, [Score=132, Expect=2e-31]} {RNA1509_1643} {WURTZEL: Gut [dd_Smed_v6_888_0_1, NA]}
13. MligTCv3c-12128.2 Mlig025766.g6 7.28 0.709 0.000

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 Mlig025766.g6 {Length: 2074} {RNA1509_12033}
14. MligTCv3c-9224.1 Mlig003938.g2 7.27 0.714 0.000

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GenAge

 ARIH2 T12E12.1 Mlig003938.g2 {Length: 5946} {TRANSSPLICED} {Pfam: IBR domain, a half RING-finger domain [PF01485.19, score=63.7]; Zinc finger, C3HC4 type (RING finger) [PF13923.4, score=20.4]} {Human: ENSG00000177479, ARIH2, ariadne homolog 2 (Drosophila), [RH, Score=413, Expect=1e-139]} {Dmel: FBgn0025186, ari-2, ariadne 2, [RH, Score=459, Expect=1e-158]} {Celegans: WBGene00020462, T12E12.1, Caenorhabditis elegans Protein T12E12.1 (T12E12.1) mRNA, complete cds., [RH, Score=392, Expect=1e-132]} {Smed: dd_Smed_v6_7986_0_1, [RH, Score=410, Expect=1e-139]} {Smes: dd_Smes_v1_67396_1_1, [RH, Score=410, Expect=1e-139]} {Smans: Smp_150890.1, [RH, Score=363, Expect=1e-119]} {UniRef: UniRef50_O76924, Potential E3 ubiquitin-protein ligase ariadne-2 n=78 Tax=Endopterygota TaxID=33392 RepID=ARI2_DROME, [Score=459, Expect=1e-156]} {RNA1509_4785}
15. MligTCv3c-9248.1 Mlig024556.g2 7.06 1.541 0.000

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 CPA2 T06A4.1 Mlig024556.g2 {Length: 1497} {SignalP} {Pfam: Zinc carboxypeptidase [PF00246.22, score=260.6]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2 (pancreatic), [Score=215, Expect=5e-65]} {Dmel: FBgn0032144, CG17633, , [RH, Score=231, Expect=2e-71]} {Celegans: WBGene00020281, T06A4.1, Caenorhabditis elegans Protein T06A4.1, isoform a (T06A4.1) mRNA, complete cds., [Score=210, Expect=9e-62]} {Smed: dd_Smed_v6_2541_0_1, [RH, Score=254, Expect=3e-80]; dd_Smed_v6_1412_0_1, [RH, Score=247, Expect=2e-77]} {Smes: dd_Smes_v1_78649_1_1, [RH, Score=254, Expect=3e-80]; dd_Smes_v1_77824_1_1, [RH, Score=248, Expect=7e-78]} {Smans: Smp_088270.1, [Score=160, Expect=5e-45]} {UniRef: UniRef50_UPI0006991870, PREDICTED: carboxypeptidase B-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI0006991870, [Score=277, Expect=2e-86]} {RNA1509_334, RNA1509_3364}
16. MligTCv3c-20415.0 Mlig001827.g2, Mlig001827.g1, Mlig001827.g3 7.05 1.060 0.000

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Mlig001827.g2 {Length: 480} {NoTransDecoderORF} {RNA1509_1854}

Mlig001827.g1 {Length: 516} {SignalP} {RNA1509_1854, RNA1509_709}

Mlig001827.g3 {Length: 596} {SignalP} {RNA1509_1764, RNA1509_709}
17. MligTCv3c-14051.1 Mlig029711.g1 6.96 1.445 0.000

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 Mlig029711.g1 {Length: 1784} {TRANSSPLICED} {SignalP} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.9, score=158.2]; Group 7 allergen [PF16984.3, score=99.3]} {Dmel: FBgn0031538, CG3246, , [Score=85.9, Expect=7e-18]} {Smed: dd_Smed_v6_888_0_1, [Score=70.9, Expect=9e-14]} {Smes: dd_Smes_v1_78416_1_1, [Score=70.5, Expect=1e-13]} {UniRef: UniRef50_UPI0006B08364, PREDICTED: uncharacterized protein LOC106459993 n=2 Tax=Limulus polyphemus TaxID=6850 RepID=UPI0006B08364, [Score=162, Expect=2e-42]} {RNA1509_13349, RNA1509_148, RNA1509_2078} {WURTZEL: Gut [dd_Smed_v6_888_0_1, NA]}
18. MligTCv3c-16860.1 Mlig013378.g2, Mlig013378.g3, Mlig013864.g2 6.93 1.152 0.000

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Mlig013378.g2 {Length: 688} {RNA1509_1137, RNA1509_491, RNA1509_924}

Mlig013378.g3 {Length: 717} {RNA1509_924}

Mlig013864.g2 {Length: 662} {RNA1509_924}
19. MligTCv3c-9248.2 Mlig024556.g1 6.9 1.560 0.000

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 CPA2 T06A4.1 Mlig024556.g1 {Length: 1510} {SignalP} {Pfam: Zinc carboxypeptidase [PF00246.22, score=262.0]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2 (pancreatic), [Score=216, Expect=2e-65]} {Dmel: FBgn0032144, CG17633, , [RH, Score=229, Expect=1e-70]} {Celegans: WBGene00020281, T06A4.1, Caenorhabditis elegans Protein T06A4.1, isoform a (T06A4.1) mRNA, complete cds., [Score=209, Expect=1e-61]} {Smed: dd_Smed_v6_2541_0_1, [RH, Score=254, Expect=2e-80]; dd_Smed_v6_1412_0_1, [RH, Score=248, Expect=6e-78]} {Smes: dd_Smes_v1_78649_1_1, [RH, Score=254, Expect=2e-80]; dd_Smes_v1_77824_1_1, [RH, Score=250, Expect=2e-78]} {Smans: Smp_088270.1, [Score=162, Expect=1e-45]} {UniRef: UniRef50_UPI0006991870, PREDICTED: carboxypeptidase B-like n=2 Tax=Lingula unguis TaxID=7574 RepID=UPI0006991870, [Score=274, Expect=2e-85]} {RNA1509_1850, RNA1509_334}
20. MligTCv3c-15475.0 Mlig018188.g1 6.87 1.077 0.000

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 Mlig018188.g1 {Length: 948} {SignalP} {RNA1509_20545, RNA1509_54742}
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